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5-Benzylidene-3-ethyl rhodanine
CAS No. 18331-34-5
5-Benzylidene-3-ethyl rhodanine( —— )
Catalog No. M20405 CAS No. 18331-34-5
5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 71 | In Stock |
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| 5MG | 110 | In Stock |
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| 10MG | 177 | In Stock |
|
| 25MG | 332 | In Stock |
|
| 50MG | 478 | In Stock |
|
| 100MG | 691 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name5-Benzylidene-3-ethyl rhodanine
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NoteResearch use only, not for human use.
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Brief Description5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
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Description5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
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In VitroBTR-1 (10, 50, 100, and 250 μM, 5 days) dose-dependently causes cytotoxicity in human leukemic cells, with IC50s of 8 and 6 μM at 48 and 72 h, respectively.Cell Viability AssayCell Line:T-cell leukemic cell lines Concentration:10, 50, 100, and 250 μM Incubation Time:5 days Result:Induced cytotoxicity in human leukemic cells in a dose-dependent manner.
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number18331-34-5
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Formula Weight249.35
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Molecular FormulaC12H11NOS2
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Purity>98% (HPLC)
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SolubilityDMSO:25 mg/mL (100.26 mM)
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SMILESCCN1C(=S)S\C(C1=O)=C/c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Moorthy B T Ravi S Srivastava M et al. Novel rhodanine derivatives induce growth inhibition followed by apoptosis[J]. Bioorganic and Medicinal Chemistry Letters 2010 20(21):6297-6301.
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